Attend a virtual event with a gout specialist on 3/19, 4/23, and 5/14
Attend a virtual event with a gout specialist on 3/19, 4/23, and 5/14
Uncontrolled gout is a serious disease and can build up in bones and joints and impact organs.* Seeing a specialist is important when gout is uncontrolled. Gout specialists are experts in diagnosing and treating uncontrolled gout.
*KRYSTEXXA has not been studied to repair damage to any of the body's organs.
Primary Care Physician
A Primary Care Physician (PCP) is typically the first contact for a person with an undiagnosed health concern. PCP Dr. Lyla Prather explains when it’s time to see a gout specialist.
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Hi, I’m Doctor Lyla Prather and I’m a primary care physician. I generally prescribe oral medications for patients with gout. If you’re taking oral medications to treat your gout and are still experiencing more than 1 flare or the presence of tophi in the last 12 months, your gout might be out of control, and it’s time for a referral to a gout specialist. Out-of-control gout can be painful, unpredictable, and cause permanent damage.
Talk to your primary care physician and ask them to refer you to a gout specialist. Gout specialists are experts in diagnosing and treating out-of-control gout. Find a gout specialist near you by entering your ZIP code in the search bar of the specialist finder.
Rheumatologist
Rheumatologists diagnose, treat, and manage various inflammatory conditions affecting muscles, joints, and bones. Rheumatologist Dr. Orrin Troum explains the impact of untreated gout.
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Hi, I’m Doctor Orrin Troum, and I’m a board-certified rheumatologist. I specialize in diagnosing and treating inflammatory diseases that affect the bones and joints, like gout.
Gout is a form of arthritis that occurs when the body has a buildup of uric acid. Not treated effectively, uric acids from gout can actually stay in your body. If you're taking oral medications and are still experiencing more than 1 flare or the presence of tophi in the last 12 months, your gout may be out of control.
Find a gout specialist near you by entering your ZIP code in the specialist finder search bar.
Nephrologist
Nephrologists diagnose, treat, and manage acute and chronic kidney diseases. Dr. Namrata Goel explains the relationship between gout and kidney disease.
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Hi, I'm Doctor Namrata Goel, and I'm a board-certified nephrologist. I specialize in conditions that affect the kidneys. About 1 in 4 people with moderate to severe kidney disease also has gout. If you are experiencing more than 1 flare or the presence of tophi in the last 12 months, while on an oral gout medication, your gout may be out of control. This occurs because diseased kidneys can have a harder time removing uric acid. If gout is left untreated, uric acid can build up in your blood and form crystals that damage your kidneys.
Find a gout specialist near you by entering your ZIP code in the specialist finder search bar.
Podiatrist
The first signs of gout typically happen in the foot. Podiatrists diagnose and treat diseases of the foot, ankle, and related leg structures. Dr. Scott Neville explains the early signs of gout and when it’s time to see a specialist.
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Hi, I'm Doctor Scott Neville, and I’m a board-certified podiatrist. I specialize in conditions that affect the feet and lower legs, including gout. Although gout can impact the entire body, it commonly starts as pain and inflammation in the foot due to buildup of uric acid crystals.
If you have more than 1 flare in the past 12 months or the presence of tophi while on oral gout medication, your gout may be out of control. Find a gout specialist near you by entering your ZIP code in the search bar of the specialist finder.
Find a specialist who understands the impact of gout and how to treat it.
Freestanding Infusion Center
Hospital Outpatient Department
Physician Office
Partner with a specialist who understands the impact of gout on the entire body.
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What is the most important information I should know about KRYSTEXXA® (pegloticase)?
Serious allergic reactions may happen in some patients who receive KRYSTEXXA. These allergic reactions can be life-threatening and usually happen within 2 hours of the infusion.
KRYSTEXXA should be given to you by a doctor or nurse in a healthcare setting where serious allergic reactions can be treated. Your doctor or nurse should watch you for any signs of a serious allergic reaction during and after your treatment with KRYSTEXXA.
Tell your doctor or nurse right away if you have any of these symptoms during or after your treatment with KRYSTEXXA:
Who should not receive KRYSTEXXA?
Do not receive KRYSTEXXA if you:
What should I tell my doctor before receiving treatment with KRYSTEXXA?
Before you receive KRYSTEXXA, tell your doctor about all of your medical conditions, including if you:
Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Do not take any other uric acid lowering drug, such as allopurinol, febuxostat (Uloric), or probenecid, while receiving KRYSTEXXA.
KRYSTEXXA is recommended to be given with another prescription medicine called methotrexate. KRYSTEXXA may also be used alone. You and your doctor will decide the treatment that is right for you.
Prior to your treatment with KRYSTEXXA, your doctor may give you medicine to help reduce your risk of getting gout flares or an allergic reaction. Take these medicines as directed by your doctor or nurse. Your doctor will also test your uric acid levels prior to each treatment to monitor your response to KRYSTEXXA.
Your gout flares may increase in the first 3 months when you start receiving KRYSTEXXA. It’s important to understand that this is happening because KRYSTEXXA is breaking down uric acid in your body. Do not stop receiving KRYSTEXXA even if you have a flare, as the amount of flares will decrease after 3 months of treatment. Your doctor may give you other medicines to help reduce your gout flares for the first few months after starting KRYSTEXXA.
What are the possible side effects of KRYSTEXXA?
In KRYSTEXXA clinical trials:
The most common side effects of
KRYSTEXXA
when given together with methotrexate were gout flares, joint pain,
coronavirus disease 2019
(COVID-19), nausea, and fatigue.
The most common side effects of KRYSTEXXA
were gout
flares, allergic reactions (including infusion reactions). See “What is the most
important information I
should know about KRYSTEXXA?”, nausea, bruising, sore throat, constipation, chest pain,
coronavirus disease
2019 (COVID-19), and vomiting.
This is not a complete list of all possible side
effects. Call your
doctor for medical advice about side effects.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/safety/medwatch or call 1-800-FDA-1088.
For additional Important Safety Information, please see the Medication Guide and discuss with your doctor.
KRYSTEXXA is a prescription medicine used in adults to help reduce the signs and symptoms of gout that are not controlled by other treatments.
KRYSTEXXA is not for use in people with too much uric acid in their bodies who do not have symptoms (asymptomatic hyperuricemia).
What is the most important information I should know about KRYSTEXXA?
Serious allergic reactions may happen in some patients who receive KRYSTEXXA. These allergic reactions can be life-threatening and usually happen within 2 hours of the infusion.
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